Oral Semaglutide is a Strategic Weapon for Diabesity in Primary Care
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GLP-1 receptor agonists (RAs) represent a highly effective category of medications for lowering glucose levels in type 2 diabetes mellitus (T2DM). According to guidelines from the European Society of Cardiology (ESC) and the European Association for the Study of Diabetes (EASD), GLP-1 RAs, such as oral semaglutide, are prioritised as initial treatments for T2D patients with cardiovascular disease (CVD) or those at heightened risk of cardiovascular events.
Additionally, they are suggested when metformin alone fails to adequately manage blood sugar levels. For individuals with T2DM aiming for weight loss or seeking to minimize the risk of hypoglycemia, or those with atherosclerotic cardiovascular disease (ASCVD) or elevated cardiovascular risk, the American Diabetes Association (ADA) recommends the utilization of GLP-1 RAs.
Unlocking the Potential of Oral Semaglutide in Primary Care
The limited uptake of GLP1RAs in primary care can be linked to some patients' reluctance towards needle-based treatments. The introduction of oral semaglutide removes a significant obstacle to therapy, providing patients with a convenient GLP-1RA choice that encourages early acceptance and improves treatment adherence. Oral semaglutide offers greater convenience and simplicity in administration compared to injections. Ultimately, it delivers considerable value to healthcare providers, patients, and their families.
HbA1c and Weight Reduction with Oral Semaglutide
A remarkable 42% increase in weight loss with oral semaglutide compared to liraglutide was observed in study (PIONEER 4 STUDY). Besides, studies (PIONEER 2 and PIONEER 3) have also demonstrated better diabetic control with an average of 1.3% reduction in HbA1c, compared with other types of anti-diabetic medication such as Empaglifozin (SGLT-2 inhibitor) (0.9% reduction in HbA1c) and Sitagliptin (DPP-4 inhibitor) (0.8% reduction in HbA1c).
Thus, oral semaglutide is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes, particularly those who are overweight or obese.
Role of Telemedicine in Diabesity
Experience enhanced diabetic control and weight loss with ease by consulting our doctors virtually to obtain oral semaglutide today! Our dedicated medical professionals will provide comprehensive guidance on the medication's indications, dosage, frequency, and potential side effects, ensuring you are fully informed. We are committed to ongoing follow-up care to monitor your progress and ensure optimal health outcomes.
References
https://www.novomedlink.com/diabetes/products/treatments/rybelsus/about/about-rybelsus.html
https://www.mims.com/malaysia/drug/info/rybelsus?type=full